![]() Their radiological appearance is also different: discrete plaques with irregular distribution for intima lesions, linear deposits for media. Calcifications of the media, known as Mönckeberg’s arteriosclerosis and mostly observed in arteries with prevalent muscle content in aging, diabetes, and CKD, are usually thin and concentric, not protruding into the arterial lumen. Calcifications of the intima develop as plaques and occlusive lesions in common atherosclerosis. VC can develop at the intima or media layers of arterial walls. ![]() Phosphatemia/Hyperphosphatemia and Vitamin K deficiency, two conditions closely related to nutrition, have been shown to be associated to VC and bone fractures in CKD. ![]() Mineral deposits on arterial walls, known as vascular calcifications (VC), are highly prevalent in aging, chronic kidney disease (CKD) and metabolic syndrome. An ongoing study will determine whether this lower MDD may reduce follow-up times to check for VC progression. We reported for the first time an estimate of MDD in VC assessment that was 25% lower for the new QC score with respect to the usual SV score. In summary, the new QC score improved the precision of lateral spine radiograph scores in estimating VC. Notably, QC and SV scores were discordant: SV showed generally higher values, and an increasing trend of differences with VC severity. Both scores were insensitive to test–retest procedure. The Minimum Detectable Difference (MDD) was smaller for QC (2.98 vs. 0.82), indicating a possible heavier learning artefact for SV. 0.64), but not in the second evaluation (0.84 vs. Inter-observer repeatability was higher for QC score in the first (Intraclass Correlation Coefficient 0.78 vs. The QC score showed higher intra-operator repeatability: the 95% CI of Bland–Altman differences was almost halved in QC intra-operator R 2 improved from 0.67 for SV to 0.79 for QC. QC results were reported in a 0–24 scale to readily compare with SV. Test–retest was performed on eight subjects. In forty-four patients with VC from an earlier study, five experts from four specialties evaluated the data twice using a dedicated software. This study tested the repeatability and reproducibility of QC score and SV score. We hypothesised that a novel continuum score based on quantitative computer-assisted tracking of calcifications (QC score) can improve the precision of the SV score. VC scores at the abdominal aorta (AA) from lateral spine radiographs are widely applied (the 0–24 semiquantitative discrete visual score (SV) being the most used). ![]() ![]() In CKD and in the elderly, Vascular Calcifications (VC) are associated to cardiovascular events and bone fractures. ![]()
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